Near 50 million or more people in US are suffering from depression and luckily many of them are fighting back. Many antidepressants are available in the market, but many of us are not sure that which brand will be suitable to fight our situation. Generic Zoloft i.e. Sertraline is one of the famous antidepressant which treats depression effectively.

Zoloft Sertraline is a selective serotonin reuptake inhibitor (SSRI) for oral administration. It has a molecular weight of 342.7. ZOLOFT Sertraline is supplied for oral administration as scored tablets containing sertraline hydrochloride equivalent to 25, 50 and 100 mg of sertraline. Sertraline is primarily used to treat major depression in adult outpatients as well as obsessive–compulsive, panic, and social anxiety disorders in both adults and children. Sertraline HCL is highly effective for the treatment of panic disorder, but cognitive behavioral therapy is a better treatment for obsessive-compulsive disorder, whether by itself or in combination with Sertraline. Although approved for social phobia and posttraumatic stress disorder, Sertraline leads to only modest improvement in these conditions. Sertraline also alleviates the symptoms of premenstrual dysphoric disorder and can be used in sub-therapeutic doses or intermittently for its treatment.

Sertraline Zoloft also treats patients suffering from panic, anxiety, obsessive compulsive symptoms, post traumatic stress disorder and premenstrual dysphoric disorder in adults over the age of 18. Children suffering from obsessive compulsive disorder and in the age group of 6-17 can be treated with this medication. Zoloft Generic can also be used in treatment of other medical conditions not listed above.

INDICATIONS AND USAGE

Major Depressive Disorder–ZOLOFT (sertraline hydrochloride) is indicated for the treatment of major depressive disorder in adults.

Obsessive-Compulsive Disorder–ZOLOFT is indicated for the treatment of obsessions and compulsions in patients with obsessive-compulsive disorder (OCD), as defined in the DSM-III-R; i.e., the obsessions or compulsions cause marked distress, are time-consuming, or significantly interfere with social or occupational functioning.

Panic Disorder– ZOLOFT is indicated for the treatment of panic disorder in adults, with or without agoraphobia, as defined in DSM-IV. Panic disorder is characterized by the occurrence of unexpected panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and/or a significant change in behavior related to the attacks.The efficacy of ZOLOFT was established in three 10-12 week trials in adult panic disorder patients whose diagnoses corresponded to the DSM-III-R category of panic disorder

Posttraumatic Stress Disorder (PTSD)–ZOLOFT (sertraline hydrochloride) is indicated for the treatment of posttraumatic stress disorder in adults.

CONTRAINDICATIONS

How to use Zoloft

Zoloft Sertraline comes as a tablet and a concentrate liquid to take by mouth. It is usually taken once daily in the morning or evening. To treat premenstrual dysphoric disorder Sertraline is taken once a day either every day of the month or on certain days of the month. To help you remember to take Sertraline take it around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take Sertraline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Before taking Zoloft:

Before taking Zoloft, tell your doctor if you have:

• liver or kidney disease;
• seizures or epilepsy;
• bipolar disorder (manic depression); or
• a history of drug abuse or suicidal thoughts.

Zoloft Precautions:

• Antidepressants may cause serious or life-threatening lung problems in newborn babies.
• During premarketing testing, hypomania or mania occurred in approximately 0.4% of ZOLOFT (sertraline hydrochloride) treated patients.
• Significant weight loss may be an undesirable result of treatment with sertraline for some patients, but on average, patients in controlled trials had minimal, 1 to 2 pound weight loss, versus smaller changes on placebo. Only rarely have sertraline patients been discontinued for weight loss.
• Mothers that have taken the medication during pregnancy however, have a relapse of depression.  
• If you are planning a pregnancy, or if you become pregnant while taking Zoloft, do not stop taking the medication without consulting your doctor.
• Do not take the liquid form of Zoloft if you are taking disulfiram (Antabuse).
• ZOLOFT has not been evaluated in patients with a seizure disorder. These patients were excluded from clinical studies during the product’s premarket testing.

Zoloft side effects:

Worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble in sleeping, impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. The most common side effects of zoloft are quick and irregular pulse, tremor, anxiety, blurred vision, vomiting, fever, diarrhea, etc.Get emergency medical help from your consultant, if you have any of these signs of an allergic reaction:

Less serious Zoloft side effects may include:

• drowsiness,
• dizziness,
• tired feeling;
• mild nausea,
• stomach pain,
• upset stomach,
• constipation;
• dry mouth;
• changes in appetite or weight;
• sleep problems (insomnia);
• decreased sex drive, impotence, or difficulty having an orgasm.

Missed dose:

• Take the missed dose as soon as you remember.
• However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed.
• Do not take extra medicine to make up the missed dose.

Overdose:

• If you think you have used too much of this medicine seek emergency medical attention right away.
• The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.
• Symptoms of a Zoloft overdose may include dizziness, drowsiness, nausea, vomiting, rapid heartbeat, agitation, tremor, confusion, seizures, and coma.

Storage:

• Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
• Do not store your drugs in the bathroom.
• Keep all drugs away from reach of children and pets.

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